Jessica Mercer (née Gardner)
Visiting Assistant Professor
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Courses Offered
- BIO 317 - Genetics
Research Interests
- The regulation of the protein TIMP-1 (tissue inhibitor of metalloproteinase-1), a known growth factor with neuroprotective properties
- Delineating signaling pathways and TIMP-1 promoter elements involved in astrocyte TIMP-1 downregulation to determine how/why this neuroprotective response fails during neuroinflammatory disease
Recent Publications
Gardner J., Borgmann K., Deshpande M.S., Dhar A., Wu L., Persidsky R., Ghorpade A. 2006. Potential mechanisms for astrocyte-TIMP-1 downregulation in chronic inflammatory diseases. Journal of Neuroscience Research 83: 1281-1292. Abstract (PubMed)
Gardner J., Ghorpade A. 2003. Tissue inhibitor of metalloproteinase (TIMP)-1: The TIMPed balance of matrix metalloproteinases in the central nervous system. Journal of Neuroscience Research 74: 801-806. Abstract (PubMed)
Last modified: August 18, 2008
