“Most institutions demand unqualified faith; but the institution of science makes skepticism a virtue.” — Robert K. Merton

Carol Fassbinder-Orth

Virology and Disease Ecology

Ph.D. – University of Wisconsin, Madison, 2008
B.S. – Iowa State University, 2003

Department of Biology
Creighton University
2500 California Plaza
Omaha, NE 68178-0103
Office: Hixson-Lied 523A
Lab: Rigge Science 526

Additional website: http://carolfassbinderorth.weebly.com/

Courses Offered

Research Interests

  • Honey Bee Health and Honey Bee Viral Dynamics
  • Alphavirus Dynamics in Cimicid Bugs and Avian Hosts
  • Ecological Immunology and Disease Ecology

Scholarly Works


Fassbinder-Orth, C. A., T. L. Killpack, D. S. Goto, E. L. Rainwater, and V. I. Shearn-Bochsler. 2018. High costs of infection: Alphavirus infection reduces digestive function and bone and feather growth in nestling house sparrows (Passer domesticus). PLoS One 13:e0195467. DOI:10.1371/journal.pone.0195467

Hofmeister, E. K., R. J. Dusek, C. Fassbinder-Orth, B. Owen, and J. C. Franson. 2016. Susceptibility and antibody response of vesper sparrows (Pooecetes gramineus) to West Nile virus: A potential amplification host in sagebrush-grassland habitat. Journal of Wildlife Diseases 52:345-353. DOI:10.7589/2015-06-148

Fassbinder-Orth, C. A., T. E. Wilcoxen, T. Tran, R. K. Boughton, J. M. Fair, E. K. Hofmeister, J. L. Grindstaff, and J. C. Owen. 2016. Immunoglobulin detection in wild birds: effectiveness of three secondary anti-avian IgY antibodies in direct ELISAs in 41 avian species. Methods in Ecology and Evolution 7:1174-1181. DOI:10.1111/2041-210X.12583

Fassbinder-Orth, C. A. 2014. Methods for quantifying gene expression in ecoimmunology: from qPCR to RNA-Seq. Integrative and Comparative Biology 54:396-406. DOI:10.1093/icb/icu023

Fassbinder-Orth, C. A., V. A. Barak, E. L. Rainwater, and A. M. Altrichter. 2014. Buggy Creek virus (Togaviridae: Alphavirus) upregulates expression of pattern recognition receptors and interferons in House Sparrows (Passer domesticus). Vector-Borne and Zoonotic Diseases 14:439-446. DOI:10.1089/vbz.2013.1531

Fassbinder-Orth, C. A., V. A. Barak, and C. R. Brown. 2013. Immune Responses of a Native and an Invasive Bird to Buggy Creek Virus (Togaviridae: Alphavirus) and its Arthropod Vector, the Swallow Bug (Oeciacus vicarius). Submitted to PLoS ONE 8:e58045. DOI:10.1371/journal.pone.0058045

Meier, S., C.A. Fassbinder-Orth, and W.H. Karasov. 2013. Ontogeny of innate immune responses in the Greater prairie-chicken (Typanuchus cupido pinnatus) and the Attwater’s prairie-chicken (Tympanuchus cupido attwateri). Journal of Wildlife Management 77:633-638. DOI:10.1002/jwmg.487.

Fassbinder-Orth, C. A., E. K. Hofmeister, C. Weeks-Levy, and W. H. Karasov. 2009. Oral and parenteral immunization of chickens (Gallus gallus) against West Nile virus with recombinant envelope protein. Avian Diseases 53:502-509.

Fassbinder-Orth, C. A., and W. H. Karasov. 2006. Effects of feed restriction and realimentation on digestive and immune function in the leghorn chick. Poultry Science 85:1449-1456.